This is a trade card for Improved Perforated Bellodonna Plaster. It is the cures for many illnesses. The front of the card has a charming illustration of 3 children, 2 girls and a boy. Love the girls bonnets, aprons and Mary Jane style of shoes.
Mitchell was born in 1837 and is the PIONEER OF PLASTER
Made at Novelty Plaster Works in Lowell, Mass at 25 cents and sold at drug stores everywhere. The bust of the man is of Mitchell and photo was done in 1864. I would guess this trade card is from 1870 to 1890.